Introduction to Structural Bioinformatics with DeepView

This module will introduce undergraduate students to structural bioinformatics using DeepView. Structural bioinformatics is a subfield of bioinformatics that centers on the structural aspects of protein and RNA sequences. DeepView is a free macromolecular visualization tool that enables the user to manipulate and analyze protein, DNA, and RNA 3D structures.


Lecture Outline

Lecture Day 1

  • Introduction to structural bioinformatics
  • Fundamentals of protein structure
  • Demonstration using DeepView

Lecture Day 2

  • Bioinformatics and evolutionary biology concepts
  • Comparative homology modeling
  • Demonstration using DeepView

 


Bioinformatics websites

Links to Structural Bioinformatics resources.

Links to Other Bioinformatics resources.

  • NCBI homepage - A resource for bioinformatics tools and databases
  • Align - Pairwise alignment tool at EBI
  • BLAST - BLAST at NCBI
  • ClustalW - Multiple sequence alignment tool and phylogenetic tree building tool at EBI
  • Tcoffee - A rigorous multiple sequence alignment tool
  • ExPASy homepage - A resource for bioinformatics tools and protein databases
  • EBI homepage - A resource for bioinformatics tools and protein databases