OK-INBRE > Core Facilities > Structural Bioinformatics

Lecture Outline

Lecture Day 1

Introduction to structural bioinformatics
Fundamentals of protein structure
Demonstration using DeepView

Lecture Day 2

Bioinformatics and evolutionary biology concepts
Comparative homology modeling
Demonstration using DeepView

Bioinformatics websites

Links to Structural Bioinformatics resources.

DeepView - A macromolecular visualization tool
RCSB Protein Data Bank - Database of protein structures
ExPASy Proteomic Tools - A list of valuable proteomics tools

Links to Other Bioinformatics resources.

NCBI homepage - A resource for bioinformatics tools and databases
Align - Pairwise alignment tool at EBI
BLAST - BLAST at NCBI
ClustalW - Multiple sequence alignment tool and phylogenetic tree building tool at EBI
Tcoffee - A rigorous multiple sequence alignment tool
ExPASy homepage - A resource for bioinformatics tools and protein databases
EBI homepage - A resource for bioinformatics tools and protein databases

Introduction to Structural Bioinformatics with DeepView

This module will introduce undergraduate students to structural bioinformatics using DeepView. Structural bioinformatics is a subfield of bioinformatics that centers on the structural aspects of protein and RNA sequences. DeepView is a free macromolecular visualization tool that enables the user to manipulate and analyze protein, DNA, and RNA 3D structures.